Oral Contributions

MS

Megan Stevens,PhD

Affiliation: School of Physiology and Pharmacology University of Bristol, Bristol (UK)
Title: Available Soon.
GC

Gennady Churakov,PhD

Affiliation: Institute for Experimental Pathology (ZMBE), University of Muenster (Germany)
Title: Available Soon.
MS

Maria Spletter,PhD

Affiliation: Dept. of Physiological Chemistry Ludwig-Maximilians-Universität München, Munich (Germany)
Title: Scaf6 (DmCHERP) regulates muscle development and function in Drosophila
IS

Iraida Sharina,PhD

Affiliation: Department of Internal Medicine/Cardiology Houston University (USA)
Title: Available Soon.
NW

Nicholas Webster,PhD

Affiliation: University of California, San Diego (USA)
Title: Lipid excess causes loss of the splicing factor SRFS3 in NAFLD and NASH
MS

Maayan Salton,PhD

Affiliation: Biochemistry and Molecular Biology Department The Institute for Medical Research Israel-Canada The Hebrew University Faculty of Medicine (Israel)
Title: Epigenetic regulation of alternative splicing in health and disease
AR

Annemieke Aartsma-Rus,PhD

Affiliation: Leiden University Medical Center, Leiden (Netherlands)
Title: Antisense-mediated splicing modulation therapy development
BE

Beatrice Eymin,PhD

Affiliation: Centre de Recherche UGA / INSERM U1209 / CNRS UMR5309 Institut Albert Bonniot (France)
Title: New functions of the splicing factor SRSF2 in DNA Damage Response
MP

Marco A.M. Prado,PhD

Affiliation: The University of Western Ontario (Canada)
Title: Cholinergic Regulation of hnRNPA2/B1
ML

Michael R. Ladomery,PhD

Affiliation: Faculty of Health and Applied Sciences University of the West of England (UK)
Title: Potent effect of the CLK1 inhibitor TG003 on prostate cancer cell growth
MM

Masafumi Matsuo,PhD

Affiliation: Faculty of Rehabilitation Kobe Gakuin University (Japan)
Title: Available Soon.
BA

Brage S. Andresen,PhD

Affiliation: University of Southern Denmark (Denmark)
Title: Available Soon.
MC

Martin Crespi,PhD

Affiliation: Institute of Plant Sciences, Bern (Switzerland)
Title: Available Soon.
JB

Jakob Biran,PhD

Affiliation: Institute of Animal Sciences Agricultural Research Organization (Israel)
Title: Available Soon.
LF

Liliana Florea ,PhD

Affiliation: McKusick-Nathans Institute of Genetic Medicine Department of Medicine/GIM Johns Hopkins School of Medicine (USA)
Title: Available Soon.
JR

Jochen Reiss,PhD

Affiliation: University Medicine Göttingen, Gottingen (Germany)
Title: Alternative splicing in molybdenum cofactor deficiency: Problems and solutions in gene therapy
CS

Christopher Sibley,PhD

Affiliation: Safra Research Fellow Division of Brain Sciences Imperial College London, London (UK)
Title: Available Soon.
MG

Michael Gotthardt,PhD

Affiliation: Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin (Germany)
Title: Available Soon.
OW

Omar Abdel-Wahab,PhD

Affiliation: Memorial Sloan Kettering Cancer Center, New York (USA)
Title: Understanding and Targeting RNA Splicing Factor Mutations in Cancer
MC

Maria Costa,PhD

Affiliation: Institut de Biologie Intégrative de la Cellule (I2BC) CNRS, CEA, Univ Paris-Sud, Université Paris-Saclay, Paris (France)
Title: Crystal Structures of a Group II Intron Lariat: Implications for Nuclear pre-mRNA Splicing
JM

Jonathan Morris,PhD

Affiliation: UNSW Sydney, Sydney (Australia)
Title: Development of Small Molecule Inhibitors of RNA Splicing Kinases
LH

Lorna Harries,PhD

Affiliation: University of Exeter (UK)
Title: Altered mRNA processing in ageing and longevity
AC

Alison Tyson-Capper,PhD

Affiliation: Institute of Cellular Medicine 3rd Floor, William Leech Building The Medical School Newcastle University (UK)
Title: Explaining why alternate splicing of the HER2 gene is so important for patients with breast cancer
GO

Gabriela N. Onganía,PhD

Affiliation: Institute of Cellular Medicine 3rd Floor, William Leech Building The Medical School Newcastle University (UK)
Title: Available Soon.
JN

John Neidhardt ,PhD

Affiliation: The National Scientific and Technical Research Council (CONICET) (Argentina)
Title: Available Soon.
AR

Antonio Rossi,PhD

Affiliation: Department of genetics, Ribeirão Preto Medical School, Universidade de São Paulo, São Paulo (Brazil)
Title: Alternative splicing in the dermatophyte Trichophyton rubrum in response to undecanoic acid.
MC

Murray Cairns,PhD

Affiliation: The National Scientific and Technical Research Council (CONICET) (Argentina)
Title: School of Biomedical Sciences and Pharmacy Faculty of Health and Medicine, Newcastle (UK)
WP

W.W.M. Pijnappel,PhD

Affiliation: Center for Lysosomal and Metabolic Diseases Erasmus Medical Center (Netherlands)
Title: GAA deficiency in Pompe disease is alleviated by exon inclusion in iPS cell-derived skeletal muscle cells
MR

Mojgan Rastegar,PhD

Affiliation: University of Manitoba (Canada)
Title: Epigenetic control and alternative splicing of MECP2 isoforms in the brain
WF

Will Fairbrother,PhD

Affiliation: Brown University (USA)
Title: The Second Life of Introns: annotating branchpoints and discovering functions of spliced introns.
TW

Thomas R. Webb,PhD

Affiliation: SRI Biosciences (USA)
Title: Available Soon.
LE

Laura Elnitski,PhD

Affiliation: National Human Genome Research Institute National Institutes of Health (USA)
Title: Deciphering splicing mutations that coincide with positions of oncogenic driver mutations
JG

Jimena Giudice,PhD

Affiliation: University of North Carolina at Chapel Hill (USA)
Title: Alternative splicing and intracellular interplay in development
PB

Patrick Burgon,PhD

Affiliation: University of Ottawa Heart Institute, Ottawa (Canada)
Title: Available Soon.
PP

Phil Potter,PhD

Affiliation: St. Jude Children’s Research Hospital (USA)
Title: Massive upregulation of alternative splicing by small molecules that target SF3B1
SF

Sonia Forcales,PhD

Affiliation: Institute of Health Research Germans Trias i Pujol (IGTP), Can Ruti Campus, Badalona, Barcelona (Spain)
Title: Aberrant binding of RNA processing proteins to a novel macrosatellite-derived lncRNA in colorectal cancer
PG

Paola Grandi,PhD

Affiliation: Cellzome GmbH, a GSK company (Germany)
Title: Click chemistry enables pre-clinical evaluation of BET inhibitor drugs
RK

Rotem Karni, PhD

Affiliation: The Hebrew University-Hadassah Medical School (Israel)
Title: Available Soon.
CM

Cameron Mackereth,PhD

Affiliation: Inserm U1212 / Univ. Bordeaux Institut Européen de Chimie et Biologie, Bordeaux (France)
Title: MEC-8 regulated alternative splicing in neurons
LD

Lourdes R Desviat,PhD

Affiliation: Universidad Autonoma de Madrid (Spain)
Title: Splicing mutations in neurometabolic diseases: mechanisms and therapies
LZ

Lingfang Zeng,PhD

Affiliation: King’s College, London (UK)
Title: A histone deacetylase 7-derived 7-amino- acid peptide acts as a phosphate group transporter
KT

Katarzyna Taylor,PhD

Affiliation: Adam Mickiewicz University, Institute of Molecular Biology and Biotechnology, Laboratory of Gene Expression (Poland)
Title: Regulation of alternative splicing by MBNL
PS

Přemysl Souček,PhD

Affiliation: CEITEC (Czech Republic)
Title: High throughput approach to identification of splicing regulatory elements in exon 7 of SMN1
RK

Rahul Kanadia,PhD

Affiliation: University of Connecticut (USA)
Title: Available Soon.
SM

Sean Porazinski Mres,PhD

Affiliation: Faculty of Health and Applied Sciences, University of the West of England (UK)
Title: Targeting the ERG oncogene with splicing switching oligonucleotides
EC

Elisabetta Castoldi,PhD

Affiliation: Department of Biochemistry, Maastricht University (The Netherlands)
Title: Regulation of coagulation by alternative splicing
LD

Luda Diatchenko, PhD

Affiliation: McGill University (Canada)
Title: Alternative Splicing of Four Opioid Receptor Genes Family Suggests an Existence of New Conserved Functional Receptor Isoforms with Unique Structure of mu Opiod Receptor MOR
AB

Andy Berglund,PhD

Affiliation: College of Medicine University of Florida (USA)
Title: The splicing factors MBNL and RBFOX co-regulate alternative splicing through multiple mechanisms
JH

James Hagman,PhD

Affiliation: Dept. of Biomedical Research National Jewish Health, University of Colorado (USA)
Title: Regulation of humoral immune responses by a novel regulator of alternative pre-mRNA splicing
IT

Ichiro Taniuchi,PhD

Affiliation: RIKEN Center for Integrative Medical Sciences (Japan)
Title: Available Soon.
EW

Eric Wang,PhD

Affiliation: University of Florida (USA)
Title: Available Soon.
RC

Russ Carstens,PhD

Affiliation: University of Pennsylvania (USA)
Title: Arhgef11 regulates RhoA-MLC mediated epidermal tight junction integrity through an alternatively spliced isoform controlled by Esrp1
SF

Sue Fletcher,PhD

Affiliation: Murdoch University Centre for Comparative Genomics (Australia)
Title: Antisense oligomer intervention increases PRPF31 expression in retinitis pigmentosa 11 studies
EB

Elizabeth Bowler,PhD

Affiliation: University of Exeter Medical School (UK)
Title: Compounds and signalling mechanisms that regulate VEGF-Axxxb splice site selection
PS

Przemyslaw Szafranski,PhD

Affiliation: Baylor College of Medicine (USA)
Title: Interrupted genes in mitochondria: a split cox2 and its expression

FB

Francois Bernier, PhD

Affiliation: University of Calgary (Canada)
Title: Craniofacial spliceosomopathies

HS

Heiner Schaal, PhD

Affiliation: Heinrich-Heine-Universität Düsseldorf (Germany)
Title: Towards understanding non-canonical 5’ splice site recognition

PJ

Peter Jordan, PhD

Affiliation: Departamento de Genética Humana, Instituto Nacional de Saúde Doutor Ricardo Jorge
(Portugal)
Title: Regulation of alternative splicing of RAC1b by signal transduction pathways
AA

Angshumonik Angbohang,PhD

Affiliation: King’s College London, London (UK)
Title: Role of XBP1 splicing in a novel type IV collagen isoform induction
NH

Natasha Hill,PhD

Affiliation: Kingston University London, London (UK)
Title: The effects of metabolic conditions on alternative splicing
RG

Roi Gazit,PhD

Affiliation: Ben-Gurion University of the Negev (Israel)
Title: Splicing in Hematopoietic Stem Cells
DE

David Elliott,PhD

Affiliation: Newcastle University (UK)
Title: Single cell transcriptome diversity by alternative splicing in human
AO

Atsushi Ogura,PhD

Affiliation: Nagahama Institute of Bioscience and Technology (Japan)
Title: Differential Alternative Splicing variants Estimation method without reference genome
TO

Takahito Ohshiro,PhD

Affiliation: Osaka University, Osaka (Japan)
Title: Development of Single-Molecule Electrical RNA Identification Method
JM

Jonathan Morris,PhD

Affiliation: UNSW Sydney, Sydney (Australia)
Title: Available Soon.
AM

Andriana Margariti,PhD

Affiliation: Queen’s University Belfast, Belfast (Ireland)
Title: Dynamic role of Quaking mRNA splicing in diabetes-related endothelial dysfunction
SB

Silvia Buonamici,PhD

Affiliation: H3 Biomedicine (USA)
Title: Available Soon.
IG

Ivan Gorlov,PhD

Affiliation: Dartmouth College (USA)
Title: Evolution of splicing and its relevance to Genome Wide Association Studies (GWAS)
MM

Milana Frenkel-Morgenstern,PhD

Affiliation: The Azrieli Faculty of Medicine Bar-Ilan University (Israel)
Title: Chimeric Protein-Protein Interaction Networks Reveal Alterations in Cancer-Specific Phenotypes
VG

Valer Gotea,PhD

Affiliation: National Human Genome Research Institute (NHGRI) (USA)
Title: An Alternative Approach to Detect Differential Exon Usage in Large RNA-Seq Datasets
RS

Ravindra Singh,PhD

Affiliation: College of Veterinary Medicine, Iowa State University (USA)
Title: Spinal muscular atrophy genes generate a vast repertoire of circular RNAs
LD

Lucy Donaldson,PhD

Affiliation: University of Nottingham (UK)
Title: Developing systemically active spicing kinase SRPK1 inhibitors as anti-inflammatory/analgesic drugs
NS

Natalia Singh,PhD

Affiliation: College of Veterinary Medicine, Iowa State University (USA)
Title: A novel role of engineered U1 snRNPs in splice site selection
MH

Marie-Louise Hammarskjold,PhD

Affiliation: University of Virginia (USA)
Title: NXF1 and Intron Retention in Viruses and Cellular Genes
BA

Boudjelal Amel,PhD

Affiliation: Msila University (Algeria)
Title: ALGERIAN TEUCRIUM POLIUM: FROM ETHNOBOTANY TO PHARMACOLOGY
MA

Mutamed Ayyash,PhD

Affiliation: College of Food and Agriculture, United Arab Emirates University (United Arab Emirates)
Title: The probiotic characterization of lactic acid bacteria isolated from dried fish product
RZ

Rui Zhao,PhD

Affiliation: University of Colorado School of Medicine (USA)
Title: Structure and function of the yeast spliceosome
LE

Luisa Escobar,PhD

Affiliation: Memorial Sloan Kettering Cancer Center (USA)
Title: Aberrant RNA splicing induced by mutant p53 promotes oncogenic RAS signaling
MC

Martin Crespi,PhD

Affiliation: Institute of Plant Sciences (France)
Title: Available Soon.
ZI

Zsuzsanna Izsvák,PhD

Affiliation: Max-Delbrück-Center for Molecular Medicine (Germany)
Title: PGBD1, a Domesticated PiggyBac-Derived Gene, has a neuroprotective Function
NP

Nicoletta Potenza,PhD

Affiliation: University of Campania “L. Vanvitelli” (Italy)
Title: Regulating the Regulators: the multifaceted story of miR-125a
WG

Wei Guo,PhD

Affiliation: Center for Cardiovascular Research and Alternative Medicine University of Wyoming (USA)
Title: Diverse Splicing Mode of a Giant Gene TTN and Its Splicing Regulation
JM

Julián Cerón Madrigal, PhD

Affiliation: Bellvitge Biomedical Research Institute – IDIBELL Hospital Duran i Reynals (Spain)
Title: Modeling splicing-related diseases by mimicking human mutations in C. elegans using CRISPR
AC

Ana Conesa, PhD

Affiliation: University of Florida (USA)
Title: Functional analysis of splicing differences between neural lineages with the tappAS tool reveals ubiquitous utilization of splicing for process regulation, but specific enrichment protein localization motifs
AK

Annelies de Klein, PhD

Affiliation: Erasmus University Medical Center (Netherlands)
Title: Uveal Melanomas with SF3B1 Mutations: A Distinct Subclass Associated with Late-Onset Metastases
UK

Ulrich Koller, PhD

Affiliation: University Hospital of the Paracelsus Medical University Salzburg, Salzburg (Austria)
Title: Col7A1 repair via RNA trans-splicing in a dystrophic epidermolysis bullosa mouse model
TL

Tao Liu, PhD

Affiliation: Children’s Cancer Institute (Australia)
Title: A evolutionarily conserved splicing variant of a novel long noncoding RNA promotes neuroblastoma
SS

Svetlana A. Shabalina, PhD

Affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health (USA)
Title: Complexity and evolution of mammalian transcriptome: the architecture of alternative transcription and splicing
GG

George A. Garinis, PhD

Affiliation: University of Crete (Greece)
Title: DNA damage and alternative splicing in development and disease
DR

David Rekosh,PhD

Affiliation: University of Virginia (USA)
Title: RNA Export of Unspliced RNA as a Modulator of HIV Replication
AR

Alexey Ruzov,PhD

Affiliation: University of Nottingham, University Park (UK)
Title: Accumulation of N6-methyladenosine on intronic DNA: RNA hybrids in human pluripotent stem cells
EK

Edor Kabashi,PhD

Affiliation: Institut du Cerveau et de la Moelle Épinière (ICM) (France)
Title: RNA-binding proteins and their role in Amyotrophic Lateral Sclerosis
YD

Yogesh Dwivedi,PhD

Affiliation: Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham (USA)
Title: Available Soon.
YA

Yann Audic,PhD

Affiliation: Institute Of Genetics And Development In Rennes, Rennes (France)
Title: Regulation of TP63 splicing
GG

Gideon Grafi,PhD

Affiliation: Ben-Gurion University of the Negev (Israel)
Title: Epigenetic silencing of the exonic Evelknievel retroelement allows for its entire splicing out and reconstitution of CMT1 mRNA
NM

Nuno Barbosa Morais,PhD

Affiliation: Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa (Portugal)
Title: CELF2 at the core of a prognostic alternative splicing signature in colorectal cancer
SG

Sylvie Tuffery-Giraud,PhD

Affiliation: Laboratoire de Génétique de Maladies Rares, IURC (France)
Title: Splicing regulation in the Duchenne Muscular Dystrophy (DMD) gene
CD

Christoph Dieterich,PhD

Affiliation: University Hospital Heidelberg German Center for Cardiovascular Research (DZHK) (Germany)
Title: Available Soon.
CR

Cosima Rhein,PhD

Affiliation: University Hospital Erlangen, Department of Psychiatry and Psychotherapy (Germany)
Title: Alternative splicing of SMPD1, coding for acid sphingomyelinase, in major depression
AB

Atze Bergsma,PhD

Affiliation: Erasmus MC (Netherlands)
Title: Available Soon.
AK

Arvydas Kanopka,PhD

Affiliation: Institute of Biotechnology, Vilnius University, Vilnius (Lithuania)
Title: Cell lines possess differential splicing factor expression and tumor associated mRNA isoform formation profiles
MS

Mikhail Skoblov,PhD

Affiliation: Research Centre for Medical Genetics (Russia)
Title: Pathogenicity analysis of nucleotide variants affecting pre-mRNA splicing in Mendelian disorders
TO

Takahito Ohshiro,PhD

Affiliation: The Institute of Scientific and Industrial Research (ISIR), Osaka University, Osaka (Japan)
Title: Development of Single-Molecule Electrical RNA Identification Method
DK

Dorota Kaminska,PhD

Affiliation: University of Eastern Finland (Finland)
Title: Analysis of obesity-related alternative splicing in adipose tissue
CH

Claude Houdayer,PhD

Affiliation: Institut Curie – Oncogenetics Head, Germline Genetics Laboratory, INSERM (France)
Title: Novel diagnostic tool for prediction of variant spliceogenicity derived from a set of 395 combined in silico/in vitro studies: an international collaborative effort
IG

Ilaria Granata,PhD

Affiliation: ICAR-CNR (Italy)
Title: Comparative analysis of alternative splicing signatures among different in vitro models of breast cancer subtypes
AL

Alexandre de Lencastre,PhD

Affiliation: Quinnipiac University (USA)
Title: Interactions between microRNAs and Splicing during C. elegans aging
GB

Glenn A. Burley,PhD

Affiliation: University of Strathclyde (UK)
Title: Unravelling the molecular determinants of splice site selection with chemical biological tools
BC

Benoit Cousineau,PhD

Affiliation: Department of Microbiology & Immunology (Canada)
Title: Bacterial group II introns generate genetic diversity at the RNA level by catalyzing intergenic trans-splicing
JC

John S.D. Chan,PhD

Affiliation: Université de Montréal, Montréal (Canada)
Title: Heterogeneous Nucleus Ribonucleoprotein F (hnRNP F) Regulates Intrarenal Renin-Angiotensin System Genes Transcription and Systemic Hypertension in Diabetes
LM

Liliana Matos,PhD

Affiliation: Instituto Nacional de Saúde Dr. Ricardo Jorge (Portugal)
Title: Development of an antisense-mediated exon skipping therapeutic strategy to correct a frequent causing mutation in Mucolipidosis II
SZ

Shao-Ling Zhang,PhD

Affiliation: University of Montréal, Montréal (Canada)
Title: Heterogeneous Nuclear Ribonucleoprotein F Deficiency Aggravates Podocyte Loss via Modulating Alternative Splicing of Insulin Receptor Gene in Adriamycin-Induced Nephropathy in Mice
RL

Raul M. Luque,PhD

Affiliation: University of Córdoba, Córdoba (Spain)
Title: Available Soon.
JC

Justo P. Castaño,PhD

Affiliation: University of Córdoba, Córdoba (Spain)
Title: Available Soon.
MG

Manuel D. Gahete,PhD

Affiliation: University of Córdoba, Córdoba (Spain)
Title: The expression of splicing machinery components can predict the development of type 2 diabetes in high-risk patients: influence of dietary intervention
DF

David J Fitzgerald,PhD

Affiliation: Henry Ford Hospital, Integrative Biosciences Center (USA)
Title: The use of an RNA-based CRISPR approach to correct aberrant RNA splicing in cells from an individual with X-linked myotubular myopathy
SA

Sophia Adamia,PhD

Affiliation: Dana-Farber Cancer Institute & HMS Medical Oncology (USA)
Title: Aberrant splicing in patients with myeloma is associated with modulated expression of PTBPs
LS

Leslie Sutherland,PhD

Affiliation: Health Sciences North Researche Institute (Canada)
Title: Identification of a complex mechanistic relationship between two related RNA binding proteins in a small cell lung cancer model
UV

Usha Vijayraghavan,PhD

Affiliation: Indian Institute of Science (India)
Title: Functions for fission yeast splicing factors in pre-mRNA splicing, alternative splice-site choice and stress-regulated splicing
XC

Xavier Roca Castella,PhD

Affiliation: Nanyang Technological University (Singapore)
Title: BIM alternative splicing as a determinant of drug responses in tyrosine kinase driven cancers